Thiamine Hydrochloride
Thiamine Hydrochloride is the hydrochloride salt form of thiamine, a water-soluble essential vitamin (Vitamin B1). It combines with adenosine triphosphate (ATP) to form thiamine pyrophosphate, a coenzyme necessary for carbohydrate metabolism, nerve function, and overall cellular energy production.
Dosage by Body Weight
Adult oral therapeutic dose for mild deficiency is typically 5 to 30 mg daily, while severe deficiency may require up to 300 mg daily. Pediatric doses should be carefully guided by a physician based on the child's specific medical needs.
- Body Weight
- Below 5 kg
- Dose
- 0.3 mg to 0.5 mg daily
- Frequency
- Once daily
- Tracking Notes
- Infant supplementation should only be given under strict pediatric guidance.
- Body Weight
- 5-7 kg
- Dose
- 0.5 mg to 1 mg daily
- Frequency
- Once daily
- Tracking Notes
- Usually met via standard infant formula or breast milk; supplement only if prescribed.
- Body Weight
- 8-10 kg
- Dose
- 1 mg to 2 mg daily
- Frequency
- Once daily
- Tracking Notes
- Monitor for any hypersensitivity reactions.
- Body Weight
- 11-15 kg
- Dose
- 2 mg to 5 mg daily
- Frequency
- Once daily
- Tracking Notes
- Doses may be adjusted upward by a clinician for metabolic or deficiency disorders.
- Body Weight
- 16-20 kg
- Dose
- 5 mg to 10 mg daily
- Frequency
- Once daily
- Tracking Notes
- Administer with food to reduce potential gastrointestinal upset.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 0.3 mg to 0.5 mg daily | Once daily | Infant supplementation should only be given under strict pediatric guidance. |
| 5-7 kg | 0.5 mg to 1 mg daily | Once daily | Usually met via standard infant formula or breast milk; supplement only if prescribed. |
| 8-10 kg | 1 mg to 2 mg daily | Once daily | Monitor for any hypersensitivity reactions. |
| 11-15 kg | 2 mg to 5 mg daily | Once daily | Doses may be adjusted upward by a clinician for metabolic or deficiency disorders. |
| 16-20 kg | 5 mg to 10 mg daily | Once daily | Administer with food to reduce potential gastrointestinal upset. |
Formulation
Purpose
Used to treat and prevent thiamine (Vitamin B1) deficiency, including conditions like beriberi, Wernicke-Korsakoff syndrome, and peripheral neuritis associated with pellagra or pregnancy.
Generic Name
Thiamine HydrochlorideBranded Drug Names
Thiamine Hydrochloride is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.